Medically reviewed by: Medical Director at First Response Healthcare Do you have difficulty in digesting certain foods or are you allergic to a particular food? Food Intolerance and Food allergy are both types of ‘food sensitivity’ and both can make one feel very ill. Quite often, it is difficult to determine whether the patient has a food intolerance or a food allergy because the signs and symptoms often overlap. Also, onset can occur quickly or only several hours after ingesting the offending food or compound and can persist for days.